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New advances in the treatment of generalized lipodystrophy: role of metreleptin

Recombinant methionyl human leptin or metreleptin is a synthetic leptin analog that has been trialed in patients with leptin-deficient conditions, such as leptin deficiency due to mutations in the leptin gene, hypothalamic amenorrhea, and lipodystrophy syndromes. These syndromes are characterized by...

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Detalhes bibliográficos
Publicado no:Ther Clin Risk Manag
Main Authors: Rodriguez, Alexander J, Mastronardi, Claudio A, Paz-Filho, Gilberto J
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577254/
https://ncbi.nlm.nih.gov/pubmed/26396524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S66521
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