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MavN is a Legionella pneumophila vacuole-associated protein required for efficient iron acquisition during intracellular growth

Iron is essential for the growth and virulence of most intravacuolar pathogens. The mechanisms by which microbes bypass host iron restriction to gain access to this metal across the host vacuolar membrane are poorly characterized. In this work, we identify a unique intracellular iron acquisition str...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Isaac, Dervla T., Laguna, Rita K., Valtz, Nicole, Isberg, Ralph R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577140/
https://ncbi.nlm.nih.gov/pubmed/26330609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511389112
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