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MavN is a Legionella pneumophila vacuole-associated protein required for efficient iron acquisition during intracellular growth

Iron is essential for the growth and virulence of most intravacuolar pathogens. The mechanisms by which microbes bypass host iron restriction to gain access to this metal across the host vacuolar membrane are poorly characterized. In this work, we identify a unique intracellular iron acquisition str...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Isaac, Dervla T., Laguna, Rita K., Valtz, Nicole, Isberg, Ralph R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577140/
https://ncbi.nlm.nih.gov/pubmed/26330609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511389112
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