Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock

Small-molecule probes have been playing prominent roles in furthering our understanding of the molecular underpinnings of the circadian clock. We previously discovered a carbazole derivative, KL001 (N-(3-(9H-carbazol-9-yl)-2-hydroxypropyl)-N-(furan-2-ylmethyl)methanesulfonamide), as a stabilizer of...

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Vydáno v:ChemMedChem
Hlavní autoři: Lee, Jae Wook, Hirota, Tsuyoshi, Kumar, Anupriya, Kim, Nam-Jung, Irle, Stephan, Kay, Steve A
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY-VCH Verlag 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576822/
https://ncbi.nlm.nih.gov/pubmed/26174033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500260
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