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The Class I-Specific HDAC Inhibitor MS-275 Decreases Motivation to Consume Alcohol and Relapse in Heavy Drinking Rats

BACKGROUND: New strategies for the treatment of alcohol dependence are a pressing need, and recent evidence suggests that targeting enzymes involved in epigenetic mechanisms seems to have great potential. Among these mechanisms, alteration of histone acetylation by histone deacetylases is of great i...

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Bibliografiske detaljer
Udgivet i:Int J Neuropsychopharmacol
Main Authors: Jeanblanc, Jerome, Lemoine, Sandrine, Jeanblanc, Virginie, Alaux-Cantin, Stéphanie, Naassila, Mickaël
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576514/
https://ncbi.nlm.nih.gov/pubmed/25762717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv029
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