The Class I-Specific HDAC Inhibitor MS-275 Decreases Motivation to Consume Alcohol and Relapse in Heavy Drinking Rats

BACKGROUND: New strategies for the treatment of alcohol dependence are a pressing need, and recent evidence suggests that targeting enzymes involved in epigenetic mechanisms seems to have great potential. Among these mechanisms, alteration of histone acetylation by histone deacetylases is of great i...

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Опубликовано в: :Int J Neuropsychopharmacol
Главные авторы: Jeanblanc, Jerome, Lemoine, Sandrine, Jeanblanc, Virginie, Alaux-Cantin, Stéphanie, Naassila, Mickaël
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576514/
https://ncbi.nlm.nih.gov/pubmed/25762717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv029
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