The Class I-Specific HDAC Inhibitor MS-275 Decreases Motivation to Consume Alcohol and Relapse in Heavy Drinking Rats

BACKGROUND: New strategies for the treatment of alcohol dependence are a pressing need, and recent evidence suggests that targeting enzymes involved in epigenetic mechanisms seems to have great potential. Among these mechanisms, alteration of histone acetylation by histone deacetylases is of great i...

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Dades bibliogràfiques
Publicat a:Int J Neuropsychopharmacol
Autors principals: Jeanblanc, Jerome, Lemoine, Sandrine, Jeanblanc, Virginie, Alaux-Cantin, Stéphanie, Naassila, Mickaël
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576514/
https://ncbi.nlm.nih.gov/pubmed/25762717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv029
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