Oligomerization of a Glucagon-like Peptide 1 Analog: Bridging Experiment and Simulations

The glucagon-like peptide 1 (GLP-1) analog, liraglutide, is a GLP-1 agonist and is used in the treatment of type-2 diabetes mellitus and obesity. From a pharmaceutical perspective, it is important to know the oligomerization state of liraglutide with respect to stability. Compared to GLP-1, liraglut...

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Udgivet i:Biophys J
Main Authors: Frederiksen, Tine M., Sønderby, Pernille, Ryberg, Line A., Harris, Pernille, Bukrinski, Jens T., Scharff-Poulsen, Anne M., Elf-Lind, Maria N., Peters, Günther H.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Proteins and Nucleic Acids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576320/
https://ncbi.nlm.nih.gov/pubmed/26340816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.051
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