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Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes
Cyclin-dependent kinases (CDKs) and their associated regulatory cyclins are central for timely regulation of cell-cycle progression. They constitute attractive pharmacological targets for development of anticancer therapeutics, since they are frequently deregulated in human cancers and contribute to...
Tallennettuna:
| Julkaisussa: | Biophys J |
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| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Biophysical Society
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576171/ https://ncbi.nlm.nih.gov/pubmed/26255588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.003 |
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