Amikacin Concentrations Predictive of Ototoxicity in Multidrug-Resistant Tuberculosis Patients

Aminoglycosides, such as amikacin, are used to treat multidrug-resistant tuberculosis. However, ototoxicity is a common problem and is monitored using peak and trough amikacin concentrations based on World Health Organization recommendations. Our objective was to identify clinical factors predictive...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Modongo, Chawangwa, Pasipanodya, Jotam G., Zetola, Nicola M., Williams, Scott M., Sirugo, Giorgio, Gumbo, Tawanda
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Clinical Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576092/
https://ncbi.nlm.nih.gov/pubmed/26248372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01050-15
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