Lumefantrine and Desbutyl-Lumefantrine Population Pharmacokinetic-Pharmacodynamic Relationships in Pregnant Women with Uncomplicated Plasmodium falciparum Malaria on the Thailand-Myanmar Border

Artemether-lumefantrine is the most widely used antimalarial artemisinin-based combination treatment. Recent studies have suggested that day 7 plasma concentrations of the potent metabolite desbutyl-lumefantrine correlate better with treatment outcomes than those of lumefantrine. Low cure rates have...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Kloprogge, Frank, McGready, Rose, Hanpithakpong, Warunee, Blessborn, Daniel, Day, Nicholas P. J., White, Nicholas J., Nosten, François, Tarning, Joel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576090/
https://ncbi.nlm.nih.gov/pubmed/26239986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00267-15
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki