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Potent In Vitro Antiproliferative Synergism of Combinations of Ergosterol Biosynthesis Inhibitors against Leishmania amazonensis

Leishmaniases comprise a spectrum of diseases caused by protozoan parasites of the Leishmania genus. Treatments available have limited safety and efficacy, high costs, and difficult administration. Thus, there is an urgent need for safer and more-effective therapies. Most trypanosomatids have an ess...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: de Macedo-Silva, S. T., Visbal, G., Urbina, J. A., de Souza, W., Rodrigues, J. C. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576079/
https://ncbi.nlm.nih.gov/pubmed/26239973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01150-15
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