A Novel Y319H Substitution in CYP51C Associated with Azole Resistance in Aspergillus flavus

This study aimed to explore any mutation in the CYP51 gene conferring azole resistance in Aspergillus flavus. Two voriconazole-resistant and 45 voriconazole-susceptible isolates were included in the study. Sequence analysis demonstrated a T1025C nucleotide change in CYP51C, resulting in the Y319H am...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Paul, R. A., Rudramurthy, S. M., Meis, J. F., Mouton, J. W., Chakrabarti, A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576050/
https://ncbi.nlm.nih.gov/pubmed/26248359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00637-15
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