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Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms and In Vivo Impact in Infected Galleria mellonella Larvae

Candida parapsilosis is the main non-albicans Candida species isolated from patients in Latin America. Mutations in the ERG11 gene and overexpression of membrane transporter proteins have been linked to fluconazole resistance. The aim of this study was to evaluate the molecular mechanisms in flucona...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Souza, Ana Carolina R., Fuchs, Beth Burgwyn, Pinhati, Henrique M. S., Siqueira, Ricardo A., Hagen, Ferry, Meis, Jacques F., Mylonakis, Eleftherios, Colombo, Arnaldo L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576033/
https://ncbi.nlm.nih.gov/pubmed/26259795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01177-15
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