Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms and In Vivo Impact in Infected Galleria mellonella Larvae

Candida parapsilosis is the main non-albicans Candida species isolated from patients in Latin America. Mutations in the ERG11 gene and overexpression of membrane transporter proteins have been linked to fluconazole resistance. The aim of this study was to evaluate the molecular mechanisms in flucona...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Souza, Ana Carolina R., Fuchs, Beth Burgwyn, Pinhati, Henrique M. S., Siqueira, Ricardo A., Hagen, Ferry, Meis, Jacques F., Mylonakis, Eleftherios, Colombo, Arnaldo L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576033/
https://ncbi.nlm.nih.gov/pubmed/26259795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01177-15
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