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Garcinia xanthochymus Benzophenones Promote Hyphal Apoptosis and Potentiate Activity of Fluconazole against Candida albicans Biofilms

Xanthochymol and garcinol, isoprenylated benzophenones purified from Garcinia xanthochymus fruits, showed multiple activities against Candida albicans biofilms. Both compounds effectively prevented emergence of fungal germ tubes and were also cytostatic, with MICs of 1 to 3 μM. The compounds therefo...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Jackson, Desmond N., Yang, Lin, Wu, ShiBiao, Kennelly, Edward J., Lipke, Peter N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576022/
https://ncbi.nlm.nih.gov/pubmed/26195512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00820-15
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