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Garcinia xanthochymus Benzophenones Promote Hyphal Apoptosis and Potentiate Activity of Fluconazole against Candida albicans Biofilms

Xanthochymol and garcinol, isoprenylated benzophenones purified from Garcinia xanthochymus fruits, showed multiple activities against Candida albicans biofilms. Both compounds effectively prevented emergence of fungal germ tubes and were also cytostatic, with MICs of 1 to 3 μM. The compounds therefo...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Jackson, Desmond N., Yang, Lin, Wu, ShiBiao, Kennelly, Edward J., Lipke, Peter N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576022/
https://ncbi.nlm.nih.gov/pubmed/26195512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00820-15
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