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Garcinia xanthochymus Benzophenones Promote Hyphal Apoptosis and Potentiate Activity of Fluconazole against Candida albicans Biofilms

Xanthochymol and garcinol, isoprenylated benzophenones purified from Garcinia xanthochymus fruits, showed multiple activities against Candida albicans biofilms. Both compounds effectively prevented emergence of fungal germ tubes and were also cytostatic, with MICs of 1 to 3 μM. The compounds therefo...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Jackson, Desmond N., Yang, Lin, Wu, ShiBiao, Kennelly, Edward J., Lipke, Peter N.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576022/
https://ncbi.nlm.nih.gov/pubmed/26195512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00820-15
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