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Identification of novel PIKFYVE gene mutations associated with Fleck corneal dystrophy

PURPOSE: To report the identification of a novel frameshift mutation and copy number variation (CNV) in PIKFYVE in two probands with fleck corneal dystrophy (FCD). METHODS: Slit-lamp examination was performed to identify characteristic features of FCD. After genomic DNA was collected, PCR amplificat...

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Publicado no:Mol Vis
Main Authors: Gee, Jessica A., Frausto, Ricardo F., Chung, Duk-Won D., Tangmonkongvoragul, Chulaluck, Le, Derek J., Wang, Cynthia, Han, Jonathan, Aldave, Anthony. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575904/
https://ncbi.nlm.nih.gov/pubmed/26396486
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