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Functional Impact of ZEB1 Mutations Associated With Posterior Polymorphous and Fuchs' Endothelial Corneal Dystrophies

PURPOSE. To assess the impact of zinc finger E-box binding homeobox 1 (ZEB1) gene mutations associated with posterior polymorphous corneal dystrophy 3 (PPCD3) and Fuchs' endothelial corneal dystrophy (FECD). METHODS. Thirteen of the 27 previously reported ZEB1 truncating mutations associated wi...

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Detalhes bibliográficos
Main Authors: Chung, Duk-Won D., Frausto, Ricardo F., Ann, Lydia B., Jang, Michelle S., Aldave, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184387/
https://ncbi.nlm.nih.gov/pubmed/25190660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15247
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