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Macrophages and Myeloid Dendritic Cells Lose T Cell-Stimulating Function in SIV Infection Associated with Diminished IL-12 and IFN-α Production()
Impaired T cell responses are a defining characteristic of HIV infection but the extent to which altered mononuclear phagocyte function contributes to this defect is unclear. We show that mononuclear phagocytes enriched from rhesus macaque lymph nodes have suppressed ability to stimulate CD4 T cell...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575859/ https://ncbi.nlm.nih.gov/pubmed/26297760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500683 |
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