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18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation

18β-Glycyrrhetinic acid (18β-GA) has been proposed as a promising hepatoprotective agent. The current study aimed to investigate the protective action and the possible mechanisms of 18β-GA against cyclophosphamide (CP)-induced liver injury in rats, focusing on the role of peroxisome proliferator-act...

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Detalhes bibliográficos
Publicado no:Genes Nutr
Main Authors: Mahmoud, Ayman M., Al Dera, Hussein S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575654/
https://ncbi.nlm.nih.gov/pubmed/26386843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-015-0491-1
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