Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer’s disease

Amyloid-beta (Aβ) plays a pivotal role in the pathogenesis of Alzheimer’s disease (AD). The physiological capacity of peripheral tissues and organs in clearing brain-derived Aβ and its therapeutic potential for AD remains largely unknown. Here, we measured blood Aβ levels in different locations of t...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol
Autors principals: Xiang, Yang, Bu, Xian-Le, Liu, Yu-Hui, Zhu, Chi, Shen, Lin-Lin, Jiao, Shu-Sheng, Zhu, Xiao-Yan, Giunta, Brian, Tan, Jun, Song, Wei-Hong, Zhou, Hua-Dong, Zhou, Xin-Fu, Wang, Yan-Jiang
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2015
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575389/
https://ncbi.nlm.nih.gov/pubmed/26363791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1477-1
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