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TBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ Cells

The T-box transcription factor TBX1 has critical roles in maintaining proliferation and inhibiting differentiation of cardiac progenitor cells of the second heart field (SHF). Haploinsufficiency of the gene that encodes it is a cause of congenital heart disease. Here, we developed an embryonic stem...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Lania, Gabriella, Ferrentino, Rosa, Baldini, Antonio
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575176/
https://ncbi.nlm.nih.gov/pubmed/26382615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138525
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