Chromatin and Transcriptional Response to Loss of TBX1 in Early Differentiation of Mouse Cells

The T-box transcription factor TBX1 has critical roles in the cardiopharyngeal lineage and the gene is haploinsufficient in DiGeorge syndrome, a typical developmental anomaly of the pharyngeal apparatus. Despite almost two decades of research, if and how TBX1 function triggers chromatin remodeling i...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Cirino, Andrea, Aurigemma, Ilaria, Franzese, Monica, Lania, Gabriella, Righelli, Dario, Ferrentino, Rosa, Illingworth, Elizabeth, Angelini, Claudia, Baldini, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505952/
https://ncbi.nlm.nih.gov/pubmed/33015063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.571501
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