AS-703026 Inhibits LPS-Induced TNFα Production through MEK/ERK Dependent and Independent Mechanisms

Chronic obstructive pulmonary disease (COPD) is characterized by intense lung infiltrations of immune cells (macrophages and monocytes). Lipopolysaccharide (LPS) activates macrophages/monocytes, leading to production of tumor necrosis factor α (TNFα) and other cytokines, which cause subsequent lung...

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發表在:PLoS One
Main Authors: Li, Ping, Wu, Yonghong, Li, Manxiang, Qiu, Xiaojuan, Bai, Xiaoyan, Zhao, Xiaojing
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575053/
https://ncbi.nlm.nih.gov/pubmed/26381508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137107
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