A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice

Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals. Mitochondrial reactive oxygen species (mtROS) have been linked to the early pathogenesis of this disorder. However, the role of mtROS remains to be evaluated due to a lack of targeted method to treat...

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Udgivet i:PLoS One
Main Authors: Wu, Jing, Li, Huihui, Sun, Xiaoru, Zhang, Hui, Hao, Shuangying, Ji, Muhuo, Yang, Jianjun, Li, Kuanyu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575031/
https://ncbi.nlm.nih.gov/pubmed/26379247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138256
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