A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice

Isoflurane possesses neurotoxicity and can induce cognitive deficits, particularly in aging mammals. Mitochondrial reactive oxygen species (mtROS) have been linked to the early pathogenesis of this disorder. However, the role of mtROS remains to be evaluated due to a lack of targeted method to treat...

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Publicat a:PLoS One
Autors principals: Wu, Jing, Li, Huihui, Sun, Xiaoru, Zhang, Hui, Hao, Shuangying, Ji, Muhuo, Yang, Jianjun, Li, Kuanyu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575031/
https://ncbi.nlm.nih.gov/pubmed/26379247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138256
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