The pharmacokinetics of peginterferon lambda-1a following single dose administration to subjects with impaired renal function

AIMS: This open label study was conducted to assess the effect of renal impairment (RI) on the pharmacokinetics (PK) of peginterferon lambda-1a (Lambda). METHODS: Subjects (age 18–75 years, BMI 18–35 kg m(–2)) were enrolled into one of five renal function groups: normal (n = 12), mild RI (n = 8), mo...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Hruska, Matthew W, Adamczyk, Robert, Colston, Elizabeth, Hesney, Michael, Stonier, Michele, Myler, Heather, Bertz, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574836/
https://ncbi.nlm.nih.gov/pubmed/25807956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12634
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