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The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity
AIMS: Atorvastatin is known to both inhibit and induce the cytochrome P450 3A4 (CYP3A4) enzyme in vitro. Some clinical studies indicate that atorvastatin inhibits CYP3A4 but there are no well-controlled longer term studies that could evaluate the inducing effect of atorvastatin. We aimed to determin...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4574832/ https://ncbi.nlm.nih.gov/pubmed/26095142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12701 |
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