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Effect of Intramuscular Protons, Lactate, and ATP on Muscle Hyperalgesia in Rats

Chronic muscle pain is a significant health problem leading to disability[1]. Muscle fatigue can exacerbate muscle pain. Metabolites, including ATP, lactate, and protons, are released during fatiguing exercise and produce pain in humans. These substances directly activate purinergic (P2X) and acid s...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Gregory, Nicholas S., Whitley, Phillip E., Sluka, Kathleen A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574767/
https://ncbi.nlm.nih.gov/pubmed/26378796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138576
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