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ASIC3 is required for development of fatigue-induced hyperalgesia

An acute bout of exercise can exacerbate pain, hindering participation in regular exercise and daily activities. The mechanisms underlying pain in response to acute exercise are poorly understood. We hypothesized that proton accumulation during muscle fatigue activates ASIC3 on muscle nociceptors to...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Gregory, Nicholas S., Brito, Renan G., Oliveira Fusaro, Maria Cláudia G, Sluka, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499332/
https://ncbi.nlm.nih.gov/pubmed/25577172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-9055-4
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