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ASIC3 is required for development of fatigue-induced hyperalgesia

An acute bout of exercise can exacerbate pain, hindering participation in regular exercise and daily activities. The mechanisms underlying pain in response to acute exercise are poorly understood. We hypothesized that proton accumulation during muscle fatigue activates ASIC3 on muscle nociceptors to...

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Vydáno v:Mol Neurobiol
Hlavní autoři: Gregory, Nicholas S., Brito, Renan G., Oliveira Fusaro, Maria Cláudia G, Sluka, Kathleen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499332/
https://ncbi.nlm.nih.gov/pubmed/25577172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-9055-4
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