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ASIC1 and ASIC3 Play Different Roles in the Development of Hyperalgesia Following Inflammatory Muscle Injury

Acid-sensing ion channels (ASICs) respond to acidosis that normally occurs after inflammation. We examined the expression of ASIC1, ASIC2, and ASIC3 mRNAs in lumbar DRG neurons before and 24h after carrageenan-induced muscle inflammation. Muscle inflammation causes bilateral increases of ASIC2 and A...

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Autores principales: Walder, R.Y., Rasmussen, L.A., Rainier, J.D., Light, A.R., Wemmie, J.A., Sluka, K.A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943154/
https://ncbi.nlm.nih.gov/pubmed/20015700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2009.07.004
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