Heterosexual Transmission of Subtype C HIV-1 Selects Consensus-Like Variants without Increased Replicative Capacity or Interferon-α Resistance

Heterosexual transmission of HIV-1 is characterized by a genetic bottleneck that selects a single viral variant, the transmitted/founder (TF), during most transmission events. To assess viral characteristics influencing HIV-1 transmission, we sequenced 167 near full-length viral genomes and generate...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Deymier, Martin J., Ende, Zachary, Fenton-May, Angharad E., Dilernia, Dario A., Kilembe, William, Allen, Susan A., Borrow, Persephone, Hunter, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574710/
https://ncbi.nlm.nih.gov/pubmed/26378795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005154
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