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Particle infectivity of HIV-1 full-length genome infectious molecular clones in a subtype C heterosexual transmission pair following high fidelity amplification and unbiased cloning

The high genetic diversity of HIV-1 impedes high throughput, large-scale sequencing and full-length genome cloning by common restriction enzyme based methods. Applying novel methods that employ a high-fidelity polymerase for amplification and an unbiased fusion-based cloning strategy, we have genera...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Deymier, Martin J., Claiborne, Daniel T., Ende, Zachary, Ratner, Hannah K., Kilembe, William, Allen, Susan, Hunter, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252503/
https://ncbi.nlm.nih.gov/pubmed/25243334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.08.018
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