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PI3Kδ Regulates the Magnitude of CD8(+) T Cell Responses after Challenge with Listeria monocytogenes

PI3Ks regulate diverse immune cell functions by transmitting intracellular signals from Ag, costimulatory receptors, and cytokine receptors to control cell division, differentiation, survival, and migration. In this study, we report the effect of inhibiting the p110δ subunit of PI3Kδ on CD8(+) T cel...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Pearce, Verity Q., Bouabe, Hicham, MacQueen, Amy R., Carbonaro, Valentina, Okkenhaug, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574522/
https://ncbi.nlm.nih.gov/pubmed/26311905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501227
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