Abnormal activation of H+ conductance in NADPH oxidase-defective neutrophils.
To combat bacterial infection, phagocytes generate superoxide (O2-) and other microbicidal oxygen radicals. NADPH oxidase, the enzyme responsible for O2- synthesis, is deficient in chronic granulomatous disease (CGD) patients. Although O2- generation is accompanied by a large burst of metabolic acid...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1993
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8421713/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.2.760 |
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