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Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli
The transcription factor NFκB is a central regulator of inflammation and genome-wide association studies in subjects with autoimmune disease have identified a number of variants within the NFκB signaling cascade. In addition, causal variant fine-mapping has demonstrated that autoimmune disease susce...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4574294/ https://ncbi.nlm.nih.gov/pubmed/26062845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa9223 |
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