Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury

BACKGROUND: Spinal cord injury (SCI) results in the activation of the NADPH oxidase (NOX) enzyme, inducing production of reactive oxygen species (ROS). We hypothesized that the NOX2 isoform plays an integral role in post-SCI inflammation and functional deficits. METHODS: Moderate spinal cord contusi...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Khayrullina, Guzal, Bermudez, Sara, Byrnes, Kimberly R.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574142/
https://ncbi.nlm.nih.gov/pubmed/26377802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0391-8
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