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Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury

BACKGROUND: Spinal cord injury (SCI) results in the activation of the NADPH oxidase (NOX) enzyme, inducing production of reactive oxygen species (ROS). We hypothesized that the NOX2 isoform plays an integral role in post-SCI inflammation and functional deficits. METHODS: Moderate spinal cord contusi...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Khayrullina, Guzal, Bermudez, Sara, Byrnes, Kimberly R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574142/
https://ncbi.nlm.nih.gov/pubmed/26377802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0391-8
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