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Prenatal allospecific NK cell tolerance hinges on instructive allorecognition through the activating receptor during development

Little is known about how the prenatal interaction between NK cells and alloantigens shapes the developing NK cell repertoire towards tolerance or immunity. Specifically, the effect on NK cell education arising from developmental co-recognition of alloantigens by activating and inhibitory receptors...

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Pubblicato in:J Immunol
Autori principali: Alhajjat, Amir M., Strong, Beverly S., Lee, Amanda E., Turner, Lucas E., Wadhwani, Ram K., Ortaldo, John R., Heusel, Jonathan W., Shaaban, Aimen F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574102/
https://ncbi.nlm.nih.gov/pubmed/26136432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500463
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