The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a rare but highly aggressive cutaneous neuroendocrine tumor. Merkel cell polyomavirus (MCPyV) may contribute to tumorigenesis in a subset of tumors via inhibition of tumor suppressors such as retinoblastoma (RB1) by mutated viral T-antigens, but the molecular pathogene...

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Udgivet i:Cancer Res
Main Authors: Harms, Paul William, Vats, Pankaj, Verhaegen, Monique Elise, Robinson, Dan R., Wu, Yi-Mi, Dhanasekaran, Saravana Mohan, Palanisamy, Nallasivam, Siddiqui, Javed, Cao, Xuhong, Su, Fengyun, Wang, Rui, Xiao, Hong, Kunju, Lakshmi P., Mehra, Rohit, Tomlins, Scott A., Fullen, Douglas Randall, Bichakjian, Christopher Keram, Johnson, Timothy M., Dlugosz, Andrzej Antoni, Chinnaiyan, Arul M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573907/
https://ncbi.nlm.nih.gov/pubmed/26238782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0702
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