IL-36γ transforms the tumor microenvironment and promotes type 1 lymphocyte-mediated antitumor immune responses

Cytokines play a pivotal role in regulating tumor immunogenicity and antitumor immunity. IL-36γ is important for the IL-23/IL-17-dominated inflammation and anti-BCG Th1 immune responses. However, the impact of IL-36γ on tumor immunity is unknown. Here, we found IL-36γ stimulated CD8(+) T cells, NK c...

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Gepubliceerd in:Cancer Cell
Hoofdauteurs: Wang, Xuefeng, Zhao, Xin, Feng, Chao, Weinstein, Aliyah, Xia, Rui, Wen, Wen, Lv, Quansheng, Zuo, Shuting, Tang, Peijun, Yang, Xi, Chen, Xiaojuan, Wang, Hongrui, Zang, Shayang, Stollings, Lindsay, Denning, Timothy L., Jiang, Jingting, Fan, Jie, Zhang, Guangbo, Zhang, Xueguang, Zhu, Yibei, Storkus, Walter, Lu, Binfeng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573903/
https://ncbi.nlm.nih.gov/pubmed/26321222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.07.014
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