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Pathogenic Mechanism of an Autism-Associated Neuroligin Mutation Involves Altered AMPA-Receptor Trafficking

Neuroligins are postsynaptic cell-adhesion molecules that bind to presynaptic neurexins. Although the general synaptic role of neuroligins is undisputed, their specific functions at a synapse remain unclear, even controversial. Moreover, many neuroligin gene mutations were associated with autism, bu...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Psychiatry
मुख्य लेखकों: Chanda, Soham, Aoto, Jason, Lee, Sung-Jin, Wernig, Marius, Südhof, Thomas C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573762/
https://ncbi.nlm.nih.gov/pubmed/25778475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.20
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