An Essential Poison: Synthesis and Degradation of Cyclic Di-AMP in Bacillus subtilis

Gram-positive bacteria synthesize the second messenger cyclic di-AMP (c-di-AMP) to control cell wall and potassium homeostasis and to secure the integrity of their DNA. In the firmicutes, c-di-AMP is essential for growth. The model organism Bacillus subtilis encodes three diadenylate cyclases and tw...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Main Authors: Gundlach, Jan, Mehne, Felix M. P., Herzberg, Christina, Kampf, Jan, Valerius, Oliver, Kaever, Volkhard, Stülke, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573722/
https://ncbi.nlm.nih.gov/pubmed/26240071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00564-15
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