Cyclic Di-AMP Homeostasis in Bacillus subtilis: BOTH LACK AND HIGH LEVEL ACCUMULATION OF THE NUCLEOTIDE ARE DETRIMENTAL FOR CELL GROWTH

The genome of the Gram-positive soil bacterium Bacillus subtilis encodes three potential diadenylate cyclases that may synthesize the signaling nucleotide cyclic di-AMP (c-di-AMP). These enzymes are expressed under different conditions in different cell compartments, and they localize to distinct po...

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Autors principals: Mehne, Felix M. P., Gunka, Katrin, Eilers, Hinnerk, Herzberg, Christina, Kaever, Volkhard, Stülke, Jörg
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548507/
https://ncbi.nlm.nih.gov/pubmed/23192352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395491
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