Single Amino Acid Polymorphisms of Pertussis Toxin Subunit S2 (PtxB) Affect Protein Function

Whooping cough due to Bordetella pertussis is increasing in incidence, in part due to accumulation of mutations which increase bacterial fitness in highly vaccinated populations. Polymorphisms in the pertussis toxin, ptxA and ptxB genes, and the pertactin, prn genes of clinical isolates of Bordetell...

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Pubblicato in:PLoS One
Autori principali: Millen, Scott H., Watanabe, Mineo, Komatsu, Eiji, Yamaguchi, Fuminori, Nagasawa, Yuki, Suzuki, Eri, Monaco, Haleigh, Weiss, Alison A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573519/
https://ncbi.nlm.nih.gov/pubmed/26375454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137379
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