Llwytho...
A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait
Several methods have been proposed to estimate the variance in disease liability explained by large sets of genetic markers. However, current methods do not scale up well to large sample sizes. Linear mixed models require solving high-dimensional matrix equations, and methods that use polygenic scor...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Am J Hum Genet |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Elsevier
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573448/ https://ncbi.nlm.nih.gov/pubmed/26189816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.06.005 |
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