Reprogramming of the Circadian Clock by Nutritional Challenge

Circadian rhythms and cellular metabolism are intimately linked. Here we reveal that a high-fat diet (HFD) generates a profound reorganization of specific metabolic pathways, leading to widespread remodeling of the liver clock. Strikingly, in addition to disrupting the normal circadian cycle, HFD ca...

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Publicat a:Cell
Autors principals: Eckel-Mahan, Kristin L., Patel, Vishal R., de Mateo, Sara, Orozco-Solis, Ricardo, Ceglia, Nicholas J., Sahar, Saurabh, Dilag, Sherry, Dyar, Kenneth A., Baldi, Pierre, Sassone-Corsi, Paolo
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573395/
https://ncbi.nlm.nih.gov/pubmed/24360271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.034
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