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Coordination of the transcriptome and metabolome by the circadian clock

The circadian clock governs a large array of physiological functions through the transcriptional control of a significant fraction of the genome. Disruption of the clock leads to metabolic disorders, including obesity and diabetes. As food is a potent zeitgeber (ZT) for peripheral clocks, metabolite...

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Autori principali: Eckel-Mahan, Kristin L., Patel, Vishal R., Mohney, Robert P., Vignola, Katie S., Baldi, Pierre, Sassone-Corsi, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325727/
https://ncbi.nlm.nih.gov/pubmed/22431615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118726109
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