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Coordination of the transcriptome and metabolome by the circadian clock
The circadian clock governs a large array of physiological functions through the transcriptional control of a significant fraction of the genome. Disruption of the clock leads to metabolic disorders, including obesity and diabetes. As food is a potent zeitgeber (ZT) for peripheral clocks, metabolite...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325727/ https://ncbi.nlm.nih.gov/pubmed/22431615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118726109 |
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