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SLFN11 is a transcriptional target of EWS-FLI1 and a determinant of drug response in Ewing’s sarcoma
PURPOSE: SLFN11 was identified as a critical determinant of response to DNA targeted therapies by analyzing gene expression and drug sensitivity of NCI-60 and CCLE datasets. However, how SLFN11 is regulated in cancer cells remained unknown. Ewing’s sarcoma (ES), which is characterized by the chimeri...
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| Publicat a: | Clin Cancer Res |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573368/ https://ncbi.nlm.nih.gov/pubmed/25779942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2112 |
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