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A pilot study of the effects of mild systemic heating on human head and neck tumour xenografts: Analysis of tumour perfusion, interstitial fluid pressure, hypoxia and efficacy of radiation therapy

PURPOSE: The tumour microenvironment is frequently hypoxic, poorly perfused, and exhibits abnormally high interstitial fluid pressure. These factors can significantly reduce efficacy of chemo and radiation therapies. The present study aims to determine whether mild systemic heating alters these para...

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Detalhes bibliográficos
Publicado no:Int J Hyperthermia
Main Authors: Winslow, Timothy B., Eranki, Annu, Ullas, Soumya, Singh, Anurag K., Repasky, Elizabeth A., Sen, Arindam
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573247/
https://ncbi.nlm.nih.gov/pubmed/25986432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02656736.2015.1037800
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