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Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia, and enhances efficacy of radiotherapy in murine tumor models
Patient and rodent solid tumors often exhibit elevated interstitial fluid pressure (IFP). This condition is recognized as a prognostic indicator for reduced responses to therapy and decreased disease-free survival. Here we tested whether induction of a thermoregulatory-mediated rise in tissue blood...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184616/ https://ncbi.nlm.nih.gov/pubmed/21512134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4482 |
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